Medical Image of the Week: Atypical Deep Sulcus Sign

Figure 1.  Chest X-ray showing hyper inflated lungs with no clear evidence of pneumothorax.

Figure 2. Atypical deep sulcus sign on the left side.

Figure 3. Complete resolution of left sided pneumothorax after chest tube placement.

The deep sulcus sign is a radiolucent lateral sulcus where the chest wall meets the diaphragm. The costophrenic angle is abnormally deepened when the pleural air collects laterally, producing the deep sulcus sign (1). Here, we present a 42-year-old man with a history of asthma who was admitted with status asthmaticus requiring intubation. On hospital day 3, the patient developed subcutaneous emphysema surrounding his entire neck and extending into left side of the chest wall. Chest X-ray after this episode showed an atypical deep sulcus sign (Figure 2) concerning for left sided pneumothorax that was also confirmed by bedside ultrasound. A surgical chest tube was placed immediately and a repeat chest X-ray (Figure 3) showed complete resolution of the pneumothorax and the deep sulcus sign. In critically ill patients where it is difficult to obtain an upright film, it is important to pay attention to the costophrenic angles when concern for pneumothorax arises. In a supine film, a deep sulcus sign may be the only indication of a pneumothorax because air collects anteriorly and basally within the nondependent portions of the pleural space, as opposed to the apex when the patient is upright (2).

Hasan Ali MD¹, Huthayfa Ateeli MBBS², Bhupinder Natt MD FACP², Sachin Chaudhary MD².

¹Department of Medicine and ²Division of Pulmonary, Critical Care, Sleep and Allergy

University of Arizona College of Medicine

Tucson, AZ USA

References

1. Kim HK, Park CY, Cho HM. Deep sulcus sign. Trauma Image & Procedure. 2016;1(1):12-3. [CrossRef]
2. Liu SY, Tsai IT, Yang PJ. Pneumothorax and deep sulcus sign. QJM. 2016;109(9):621-2. [CrossRef] [PubMed]  

Cite as: Ali H, Ateeli H, Natt B, Chaudhary S. Medical image of the week: atypical deep sulcus sign. Southwest J Pulm Crit Care. 2018;16(4):224-5. doi: https://doi.org/10.13175/swjpcc044-18 PDF 

February 2018 Imaging Case of the Month

Michael B. Gotway, MD

Department of Radiology

Mayo Clinic Arizona

Scottsdale, AZ USA

Clinical History: An 18-year-old woman with a questionable history of asthma (one physician source claimed no clear history of asthma, whereas another source claimed severe asthma) presented to the emergency room with worsening shortness of breath and cough. The patient’s past medical history was otherwise largely unremarkable. She did have complaints of recurrent rhinorrhea and allergies, for which sinus CT (Figure 1) had been performed.

Figure 1. Unenhanced axial sinus CT shows multifocal sinus opacification (arrow = maxillary sinuses, arrowheads = ethmoid sinuses, double arrowhead= sphenoid sinus)

Physical examination was remarkable for coarse, right-greater-than-left basal rales and coarse breath sounds. The patient’s oxygen saturation was 98% on room air. Her nasal septum appeared deviated. The patient’s vital signs were within normal limits and she was afebrile.

Laboratory evaluation showed a normal complete blood count, electrolyte panel, and liver function tests. A digital frontal chest image (Figure 2) obtained at presentation is shown, with a comparison chest radiograph from 5 months earlier also shown.

Figure 2. A: Digital frontal chest image. B: Chest radiograph from 5 months earlier.

Which of the following represents the most accurate assessment of the frontal chest imaging findings? (Click on the correct answer to proceed to the second of seven pages)

1. Chest frontal imaging shows basilar fibrosis
2. Chest frontal imaging shows mediastinal and peribronchial lymphadenopathy
3. Chest frontal imaging shows multiple, bilateral small nodules
4. Chest frontal imaging shows normal findings
5. Chest frontal imaging shows patchy nodular opacities in the right lung

Cite as: Gotway MB. February 2018 imaging case of the month. Southwest J Pulm Crit Care. 2018;16(2):67-75. doi: https://doi.org/10.13175/swjpcc019-18 PDF

Medical Image of the Week: Plastic Bronchitis

Figure 1. Cast removed from the right main stem.

Figure 2. Casts removed from right lower lobe.

Plastic Bronchitis is a rare syndrome characterized with expectoration of bronchial casts.  Conditions associated with plastic bronchitis in adults include asthma, allergic bronchopulmonary aspergillosis, cystic fibrosis, bronchiectasis, tuberculosis, amyloidosis, sickle cell anemia and rheumatoid arthritis. In children, is its associated with congenital heart diseases (1).

Typical casts are large and branched. These can be expectorated or removed endoscopically as in our case of a 52-year old man with respiratory failure (Figures 1 and 2). The exact etiology of his plastic bronchitis remains obscure. These casts were removed using a bronchoscope with a cryotherapy probe. 

Lauren Estep MD and Bhupinder Natt MD FACP

Division of Pulmonary, Allergy, Critical Care and Sleep

Banner-University Medical Center, Tucson, AZ USA

Reference

1. Itkin MG, McCormack FX, Dori Y. Diagnosis and treatment of lymphatic plastic bronchitis in adults using advanced lymphatic imaging and percutaneous embolization. Ann Am Thorac Soc. 2016 Oct;13(10):1689-96. [CrossRef] [PubMed]

Cite as: Estep L, Natt B. Medical image of the week: plastic bronchitis. Southwest J Pulm Crit Care. 2018;16(1):28. doi: https://doi.org/10.13175/swjpcc005-18 PDF 

Medical Image of the Week: A Positive Methacholine Challenge

Figure 1. Positive methacholine challenge. The patient had a 39% drop in FEV1 after inhalation of 0.0625 mg/dL of methacholine, the lowest concentration tested. The drop in FEV1 was reversed by a bronchodilator (Post BD).

A methacholine challenge test is one of the methods to assess bronchial hyperresponsiveness (BHR). BHR is one of the features that can contribute to the diagnosis of asthma. The test is reported as a PC-20 value; the inhaled provocative concentration causing a 20% drop or more in the pretest FEV1. This patient had a PC-20 of <0.1 mg/mL which is interpreted as a moderate to severe bronchial hyperresponsiveness by ATS guidelines (1). A normal bronchial response is a PC-20 > 16 mg/ml, 4-16 mg/mL is considered borderline and 1-4 mg/mL is mild BHR according to the ATS guidelines.

Mohammad Dalabih, MBBS and Linda Snyder, MD

University of Arizona

Tucson, AZ USA

Reference

1. Crapo RO, Casaburi R, Coates AL, Enright PL, Hankinson JL, Irvin CG, MacIntyre NR, McKay RT, Wanger JS, Anderson SD, Cockcroft DW, Fish JE, Sterk PJ. Guidelines for methacholine and exercise challenge testing-1999. Am J Respir Crit Care Med. 2000 Jan;161(1):309-29.

Cite as: Dalabih M, Snyder L. Medical image of the week: a positive methacholine challenge. Southwest J Pulm Crit Care. 2016 Apr;12(4):152. doi: http://dx.doi.org/10.13175/swjpcc017-16 PDF

Medical Image of the Week: Finger in Glove

Figure 1. PA (Panel A) and lateral (Panel B) chest x-ray showing finger in glove (arrow) in the right upper lung with other scattered areas of consolidation.

Figure 2. Repeat chest x-ray about a month later showing generalized clearing.

A 45-year old man with a history of asthma presented with increasing shortness of breath, and cough productive of dark firm plugs, sometimes branching. His chest x-ray (Figure 1) shows finger in glove (arrow) in the right upper lung with other scattered areas of consolidation. His serum IgE was elevated at 750 IU/ml (normal < 380 IU/ml).  His eosinophil count was 12%.   Aspergillus IgE was 6.69 (normal< 0.35). A diagnosis of probable allergic bronchopulmonary aspergillosis (ABPA) was made. He was given oral corticosteroids. Follow up about a month later showed dramatic clinical improvement and a repeat chest x-ray (Figure 2) showed generalized clearing.

The initial chest x-ray shows a “finger in glove” pattern in the right upper lobe (Figure 1, arrow), which is due to mucoid impaction within the larger bronchi (1). The same appearance has also been referred to as the rabbit ear appearance, Mickey Mouse appearance, toothpaste-shaped opacities, Y-shaped opacities, V-shaped opacities and the Churchill sign because it resembles the “V” gesture often associated with Winston Churchill.

ABPA is an immunological pulmonary disorder caused by hypersensitivity to Aspergillus fumigatus, manifesting with poorly controlled asthma, recurrent pulmonary infiltrates and central bronchiectasis (2). Primary therapy consists of oral corticosteroids to control exacerbations, itraconazole as a steroid-sparing agent and optimized asthma therapy. Uncertainties surround the prevention and management of bronchiectasis, chronic pulmonary aspergillosis and aspergilloma as complications, concurrent rhinosinusitis, environmental control and long-term management.

Gerald F. Schwartzberg, MD

Phoenix, AZ

References

1. Weerakkody Y, Jones J. Finger in glove sign. Available at: http://radiopaedia.org/articles/finger-in-glove-sign (accessed 11/22/13).
2. Agarwal R, Chakrabarti A, Shah A, Gupta D, Meis JF, Guleria R, Moss R, Denning DW; ABPA complicating asthma ISHAM working group. Allergic bronchopulmonary aspergillosis: review of literature and proposal of new diagnostic and classification criteria. Clin Exp Allergy. 2013;43(8):850-73. [CrossRef] [PubMed]

Reference as: Schwartzberg GF. Medical image of the week: finger in glove. Southwest J Pulm Crit Care. 2014:8(1):64-5. doi: http://dx.doi.org/10.13175/swjpcc169-13 PDF

June 2013 Imaging Case of the Month

Michael B. Gotway, MD

Department of Radiology

Mayo Clinic Arizona

Scottsdale, AZ

Clinical History

A 42-year-old woman complained of cough and intermittent wheezing with shortness of breath. Her previous medical history was unremarkable. Frontal and lateral (Figures 1A and B) chest radiography was performed.

Figure 1. Frontal (Panel A) and lateral (Panel B) chest x-ray.

Which of the following statements regarding the chest radiograph is most accurate?

1. The chest radiograph shows no abnormalities
2. The chest radiograph shows bilateral, basal reticulation suggesting fibrotic lung disease
3. The chest radiograph shows medial left lower lobe opacities
4. The chest radiograph shows large lung volumes associated with faint cystic change
5. The chest radiograph shows numerous small nodules suggesting a miliary pattern 

Reference as: Gotway MB. June 2013 imaging case of the month. Southwest J Pulm Crit Care. 2013;6(6):263-71. PDF